Lizzy Caplan

Biography

Elizabeth Anne Caplan (born June 30, 1982) is an American actress. Her performances as Virginia E. Johnson in the Showtime series Masters of Sex (2013–2016) and as Libby Epstein in FX on Hulu's Fleishman Is in Trouble (2022) have earned her nominations at the Primetime Emmy Awards. Her first acting role was on the television series Freaks and Geeks (1999–2000). Since then, she had series-regular roles in several television series including Related (2005–2006), Party Down (2009–2010; 2023), Das Boot (2018), Castle Rock (2019), Truth Be Told (2019), Fatal Attraction (2023), and Zero Day (2025). Caplan's film breakthrough came with her role as Janis Ian in Mean Girls (2004). Her other film appearances include My Best Friend's Girl (2008) Cloverfield (2008), Hot Tub Time Machine, 127 Hours (both 2010), Save the Date, Bachelorette (both 2012), The Interview (2014), Now You See Me 2, Allied (both 2016), and Cobweb (2023). Description above from the Wikipedia article Lizzy Caplan, licensed under CC-BY-SA, full list of contributors on Wikipedia.

Known For

The Simpsons

Family Guy

The Tonight Show Starring Jimmy Fallon

Watch What Happens Live with Andy Cohen

Smallville

American Dad!

Late Night with Seth Meyers

Conan

All Movies (35)

• Drag2026
• Now You See Me: Now You Don't2025 · as Lula
• Cobweb2023 · as Carol
• The People We Hate at the Wedding2022 · as Marissa
• 7 Up & Me2019 · as Self
• The Toll Road2019 · as Emily
• Extinction2018 · as Alice
• The Disaster Artist2017 · as Lizzy Caplan
• Allied2016 · as Bridget Vatan
• Now You See Me 22016 · as Lula
• The Night Before2015 · as Diana
• The Interview2014 · as Agent Lacey
• Beef2014 · as Audrey
• The Sidekick2013 · as Bailey
• Save the Date2012 · as Sarah
• 3, 2, 1... Frankie Go Boom2012 · as Lassie
• Marvel One-Shot: Item 472012 · as Claire Wise
• Queens of Country2012 · as Jolene Gillis
• High Road2012 · as Sheila
• Bachelorette2012 · as Gena Myers
• Home for Actresses2011 · as Lizzy
• 127 Hours2010 · as Sonja Ralston
• The Last Rites of Ransom Pride2010 · as Juliette Flowers
• Hot Tub Time Machine2010 · as April
• Successful Alcoholics2010 · as Lindsay
• Crossing Over2009 · as Marla
• My Best Friend's Girl2008 · as Ami
• Cloverfield2008 · as Marlena
• Crashing2007 · as Jacqueline
• Love Is the Drug2006 · as Sara Weller
• Mean Girls2004 · as Janis Ian
• Hardcore Action News2003 · as Lizzy Lyons
• Everybody's Doing It2002 · as Angela
• Orange County2002 · as Party Girl
• From Where I Sit2000 · as Lily

All TV Shows (42)

• Zero Day2025 · as Alexandra Mullen
• Fatal Attraction2023 · as Alex Forrest
• Fleishman Is in Trouble2022 · as Libby Epstein
• Inside Job2021 · as Reagan Ridley (voice)
• Truth Be Told2019 · as Lanie Buhrman / Josie Buhrman
• Das Boot2018 · as Carla Monroe
• Castle Rock2018 · as Annie Wilkes
• Ill Behaviour2017 · as Nadia
• Chelsea2016 · as Self
• Angie Tribeca2016 · as Deirdre
• Close Up with The Hollywood Reporter2015 · as Self
• Late Night with Seth Meyers2014 · as Self - Guest
• The Tonight Show Starring Jimmy Fallon2014 · as Self
• Off Camera with Sam Jones2014 · as Self
• Masters of Sex2013 · as Virginia Johnson
• The Last Leg2013 · as Self
• Comedy Bang! Bang!2012 · as Self
• New Girl2011 · as Julia Cleary
• Mr. Sunshine2011 · as Vivian Cornelli
• Conan2010 · as Self
• The League2009 · as Rebecca Ruxin
• The Cleveland Show2009
• Watch What Happens Live with Andy Cohen2009 · as Self - Guest
• Party Down2009 · as Casey Klein
• Childrens Hospital2008 · as Casey Klein
• Childrens Hospital2008 · as Harmony
• True Blood2008 · as Amy
• The Class2006 · as Kat Warbler
• Related2005 · as Marjee Sorelli
• American Dad!2005 · as Debbie (voice)
• Tru Calling2003 · as Avery Bishop
• The Pitts2003 · as Faith Pitt
• Jimmy Kimmel Live!2003 · as Self
• Jimmy Kimmel Live!2003 · as Self - Guest
• Smallville2001 · as Tina Greer
• Undeclared2001 · as Beautiful Girl
• Freaks and Geeks1999 · as Sara
• Once and Again1999
• Family Guy1999 · as Woman Arguing With Quagmire (voice)
• The View1997 · as Self
• The Simpsons1989 · as Virginia Johnson (voice)
• The Boys from Brazil— · as Hannah Liebermann